Skin is the body’s largest organ, and therefore directly impacted by chronic hyperglycaemia. Sweat and sebum glands, nerves and arteries can all be affected, and the skin can suffer in different ways.
Diabetes’ effect on skin can therefore be far-reaching. It’s possible that the skin’s sweat and sebum glands secrete less. This can lead to dry and very dry skin. Particularly in feet, extra thick skin – hyperkeratosis – may also develop. When chemical reactions in nerve endings create nerve damage, muscles in the foot may atrophy, leading to deformations such as a flat foot or hammer toes. Feet or a part of the foot may lose all sensation. When arteries are affected, blood no longer flows correctly, depriving areas of the body of oxygen, which is required for proper healing.