The sugar in the bloodstream creates complications throughout the body. With skin being the body’s largest organ, "high sugar levels create stress in the skin’s layers. The sugar creates chemical reactions in nerve endings, which no longer fulfil their role of distributing information."
Patients can develop dry skin, hyperkeratosis (thick skin) and also artery problems, all associated to high blood sugar levels. "Often, patients aren’t even aware that these problems are a result of their diabetes.".
When these problems move to feet, a number of complications can occur. "Diabetic foot problems are a medical syndrome all on their own, that affect a quarter of all diabetics," Cindy Bouché notifies." They start when there is either a nerve and/or arterial problem that already exists, plus a triggering factor. A cascade of events can occur which, if not quickly cared for, can have dramatic consequences."